Cell Behavior Regulation

Modifying the Behavior of Cultured Meat Relevant Cells Without Alterations to the Genome

New Harvest Research Fellow: John Yuen, PhD Candidate, Biomedical Engineering, Tufts University

Project Start Date: December 2018

Project Duration: Full time; Four years funded; One year optional extra for completion.

Institutes: Tufts University, Boston, MA, USA; NIH P41 Tissue Engineering Resource Center, Boston, MA, USA

Supervisors: Dr. David Kaplan (Professor/Chair, Biomedical Engineering; Tufts University)​​:

Project Abstract: 

John is working on managing the behavior of cells used in cultured meat production to make them usable in large scale production. This involves processes such as preventing cellular senescence (where cells stop multiplying) and promoting robust stem cell differentiation into muscle fibers. John is trying to achieve these goals without genomic modifications, as this may assist in the acceptance of cultured meat in regions of the world that are typically against genetic modification in food, such as the European Union (EU).